< Back

Biomedical fluid mechanics

Pulsating, unsteady bio-fluid flows in complex geometries, from aortic and cardiac devices to filler injection

Together with our colleagues and medical doctors, we study the fluid dynamics of pulsating, unsteady flows in complex geometries, helping health professionals better understand the effect of fluid motion and fluid-structure interaction in vascular disease, body fluid drainage and other clinical questions.

We work with aorta flows, TAVI, heart valves, ventricular assist devices, cerebrospinal fluid models, coronary trees, and more. Our speciality is three-dimensional, time-varying flows and Lagrangian tracking, which are especially useful in transparent physical replicas of complex human geometry.

Our most recent project applies 3D-PTV to a transparent phantom model of the left ventricle. The main goal is to relate the wall shear stress on the ventricle wall to the flow patterns we observe, since wall shear stress is a key mechanical signal in cardiac tissue remodeling.

Selected publications

I. Avrahami, D. Kersh, A. Liberzon (2016), "Pulsatility Index as a Diagnostic Parameter of Reciprocating Wall Shear Stress Parameters in Physiological Pulsating Waveforms", PLOS ONE.

T. Yeshurun, Y. Bar David, A. Herman, S. Bar-Sheshet, R. Zilberman, G. Bachar, A. Liberzon, G. Segev (2020), "A simulation of a medical ventilator with a realistic lungs model", F1000Research.

I. Kogan, P. Korolik, H. Cartier, H. Adhoute, A. Liberzon (2020), "In vitro evaluation of aspiration of hyaluronic acid filler with a new saline flashing method", Journal of Cosmetic Dermatology.